Inside the science
1
Discover your bloating type:
A short quiz helps identify which of three bloating types fits best.
Each type reflects a different way the gut behaves, including how well it moves.
The full program is built around that type. Everything inside is specific and relevant.
2
Three Phases. 16 Weeks.
The program is delivered week by week in three clear phases, with gut motility as a core focus throughout.
Phase 1: Remove Weeks 1–8
Plant-based antimicrobials, digestive support, and motility activation to start clearing the imbalance and get the gut moving again.
Phase 2: Rebuild Weeks 9–12
Targeted probiotics, beneficial yeast, and gut-lining nutrients to restore balance while keeping motility on track.
Phase 3: Maintain Weeks 13–16
Ongoing motility support, smarter eating, and habits that keep bloating from coming back. A gut that moves well is a gut that stays well.
3
Track Progress with a Weekly Log
A weekly symptom log runs alongside the program. It builds a clearer picture of what affects digestion and gut movement over time.
Tracking responses to food, stress, sleep, and other factors helps connect the dots between daily habits and how the gut feels and functions.
✓
Science-Backed.
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Motility-Focused.
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Easy to Understand.
The research behind each phase
Phase 1: Remove
- Berberine, one of the core compounds in this phase, was shown in a trial of over 400 people to reduce harmful gut bacteria while helping beneficial ones grow. It also supports the production of short-chain fatty acids, which are essential for gut lining health and normal motility.
- Oregano and thyme contain carvacrol, a powerful antimicrobial compound that disrupts bacteria cell membranes and interferes with bacterial communication. These work alongside NAC (N-acetylcysteine), one of the most effective biofilm disruptors available. NAC breaks down the protective shields bacteria build around themselves, making them vulnerable to antimicrobials. Research shows that combining antimicrobials with biofilm disruptors works significantly better than antimicrobials alone.
- Motility support starts here too. When bacterial overgrowth slows the gut down, clearing the imbalance is the first step to getting movement back on track. Phase 1 pairs antimicrobial action with prokinetic support so the gut starts moving while it starts clearing.
Zhang Y et al. Nature Communications. 2020 · Zhang et al. Frontiers in Cellular and Infection Microbiology. 2021 · Ruscio et al. Cureus. 2025 · Moghrovyan & Sahakyan. AIMS Biophysics. 2024
A 2014 Landmark
Science has known since 2014 that herbal antimicrobials perform comparably to pharmaceutical antibiotics in resolving microbiome imbalances, and subsequent studies have continued to confirm it.
Chedid et al. Global Advances in Health and Medicine. 2014
Phase 2: Rebuild
Once the gut environment shifts, rebuilding happens on three fronts simultaneously. Spore-based probiotics have been shown to increase the diversity of beneficial bacteria and support the production of compounds that feed the gut lining. Research shows that L-glutamine restores tight junction protein expression in the intestinal lining, while zinc carnosine provides direct mucosal protection through antioxidative and membrane-stabilizing mechanisms, strengthening the gut barrier from two distinct pathways. Research on ginger and artichoke extracts shows they significantly improve gut motility, helping food and bacteria move through the digestive tract the way they should, which is essential for keeping the gut environment stable after the first phase.
Marzorati et al. Food Research International. 2021 / Zhou et al. Gut. 2019 / Efthymakis & Neri. Clinical Research in Hepatology and Gastroenterology. 2022 / Drobnic et al.
Minerva Gastroenterology. 2022
Phase 3: Maintain
Sustaining microbiome balance requires expanding diversity, not maintaining a fixed protocol. A 17-week randomized study found that consistently eating fermented foods steadily increased microbiome diversity and reduced 19 inflammatory markers over time. Data from two large prospective cohorts confirm that greater variety across plant food groups is independently associated with higher gut microbiome diversity, which is why rotating fiber types like resistant starches, inulin-type fructans, and beta-glucans matters: each feeds distinct bacterial populations that a single source cannot reach. A systematic review of 13 human studies found that psychological stress is consistently associated with significant reductions in specific beneficial bacterial groups at the genus level, making lifestyle consistency as important as any dietary input in preserving what the earlier phases built.
Wastyk et al. Cell. 2021 / Xiao et al. American Journal of Clinical Nutrition. 2022/ Ma et al. Neuropsychobiology. 2023
Got questions? We have answers
Who is the AlloBiome program for?
AlloBiome is for people who experience chronic bloating, irregular digestion, or other persistent gut symptoms and want to understand what science currently knows about those patterns. This is not a medical service and does not replace professional care. It is a science education resource for people who are tired of generic advice and want real answers backed by real research.
What is microbiome pattern education?
It is not a course or a class. It is a living body of scientific knowledge, continuously synthesized from thousands of peer-reviewed studies by Al and reviewed by the NEIMS research team. The content goes far beyond surface-level information. It covers fermentation dynamics, motility research, gut ecosystem science, and what current studies say about specific supplements, including the evidence behind doses, timing, and ingredient quality. The NEIMS team has the tools and infrastructure to evaluate brands and ingredients properly, so the science presented reflects what is actually supported in the literature, not just what is marketed well.
How does the daily symptom diary work?
The diary is an awareness tool, not a treatment tracker. It helps build a clearer picture of personal digestive patterns over time by observing how symptoms relate to food, stress, sleep, and other factors. AlloBiome does not interpret diary data or provide any form of assessment or guidance based on it.
Does AlloBiome address other digestive patterns?
The current program focuses on the pattern identified through the quiz. The NEIMS research team continuously reviews emerging research, and additional educational content may be added as the science develops.
How is the program content delivered?
Content is released week by week across three phases: Remove, Rebuild, and Maintain. This is not a passive library to scroll through. The
progressive structure ensures the information arrives when it is most relevant, covering what researchers currently know about each phase of gut recovery, from antimicrobial compounds and biofilm disruption to probiotic strains, gut lining support, and long-term microbiome maintenance. Everything is broken down so it is easy to absorb and relevant to where someone actually is in their learning.
How long is the program ?
The program spans 16 weeks across three phases, with the final phase designed as an ongoing practice. The goal is long-term understanding, not a quick fix.
What research sources does the NEIMS team use?
The NEIMS team draws from peer-reviewed journals in gastroenterology, microbiology, and nutritional science, prioritizing recent studies and established researchers in the microbiome field. Beyond reading the literature, the team has the infrastructure to evaluate the actual quality of supplement ingredients, specific strain research, bioavailability data, and brand manufacturing standards. AlloBiome does not generate its own clinical claims. Everything presented reflects what the published science currently supports.
Who is behind AlloBiome and NEIMS?
AlloBiome is developed by NEIMS (New England Institute of Microbiome Science), a research institute dedicated to translating gut health science into accessible education. The team includes a board-certified Medical Laboratory Scientist (MLS) with clinical, research, and laboratory expertise as Research Director, a Ph.D. researcher with published work in scientific writing, data analysis, and peer-reviewed methodology, and multiple research assistants supporting ongoing literature review and content development. The team leverages Al technology to process and synthesize thousands of peer-reviewed papers at a speed and scale that traditional research teams cannot match. This allows the NEIMS team to stay current with emerging science daily while maintaining full editorial oversight of all published content.
References
- Zhang, Y., Gu, Y., Ren, H., Wang, S., Zhong, H., Zhao, X., … & Jia, W. (2020). Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study). Nature Communications, 11, 5015. https://doi.org/10.1038/s41467-020-18414-8
- Zhang, L., Wu, X., Yang, R., Chen, F., Liao, Y., Zhu, Z., Wu, Z., Sun, X., & Wang, L. (2021). Effects of Berberine on the Gastrointestinal Microbiota. Frontiers in Cellular and Infection Microbiology, 10, 588517. https://doi.org/10.3389/fcimb.2020.588517
- Moghrovyan, A., & Sahakyan, N. (2024). Antimicrobial activity and mechanisms of action of Origanum vulgare L. essential oil: effects on membrane-associated properties. AIMS Biophysics, 11(4), 508-526. https://doi.org/10.3934/biophy.2024027
- Chedid, V., Dhalla, S., Clarke, J. O., Roland, B. C., Dunbar, K. B., Koh, J., Justino, E., Tomakin, E., & Mullin, G. E. (2014). Herbal therapy is equivalent to rifaximin for the treatment of small intestinal bacterial overgrowth. Global Advances in Health and Medicine, 3(3), 16-24. https://doi.org/10.7453/gahmj.2014.019
- Ruscio, M., Lukens, B., & D’Adamo, C. R. (2025). Biofilm disruption combined with herbal antimicrobials in small intestinal bacterial overgrowth. Cureus. https://doi.org/10.7759/cureus
- Marzorati, M., Van den Abbeele, P., Bubeck, S., Bayne, T., Krishnan, K., & Young, A. (2021). Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME model. Food Research International, 149, 110676. https://doi.org/10.1016/j.foodres.2021.110676
- Zhou, Q., Verne, M. L., Fields, J. Z., Lefante, J. J., Basra, S., Salameh, H., & Verne, G. N. (2019). Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut, 68(6), 996-1002. https://doi.org/10.1136/gutjnl-2017-315136
- Efthymakis, K., & Neri, M. (2022). The role of Zinc L-Carnosine in the prevention and treatment of gastrointestinal mucosal disease in humans: a review. Clinics and Research in Hepatology and Gastroenterology, 46(7), 101954. https://doi.org/10.1016/j.clinre.2022.101954
- Drobnic, F., Fonts, S., García-Alday, I., Petrangolini, G., Riva, A., Frattini, E., Allegrini, P., Togni, S., & Vitale, J. (2022). Efficacy of artichoke and ginger extracts with simethicone to treat gastrointestinal symptoms in endurance athletes: a pilot study. Minerva Gastroenterologica (Torino), 68(1), 77–84. https://doi.org/10.23736/S2724-5985.20.02664-1
- Wastyk, H. J., Fragiadakis, G. K., Perelman, D., Dahl, W. J., Merrill, B. D., Yu, F. B., Topf, M., Gonzalez, J. G., Van Treuren, W., Hahn, S., Robinson, J. L., Elias, J. E., D. D., Ener, D. Garner, & D. Son. Sonnenburg, J. L. (2021). Gut-microbiota-targeted diets modulate human immune status. Cell, 184(16), 4137- 4153.e14. https://doi.org/10.1016/j.cell.2021.06.019
- Ma, L., Yan, Y., Webb, R. J., Li, Y., Mehrabani, S., Xin, B., Sun, X., Wang, Y., & Mazidi, M. (2023). Psychological stress and gut microbiota composition: a systematic review of human studies. Neuropsychobiology, 82(5), 247-262. https://doi.org/10.1159/000533131
- Xiao, C., Wang, J. T., Su, C., Miao, Z., Tang, J., Ouyang, Y., Yan, Y., Jiang, Z., Fu, Y., Shuai, M., Gou, W., Xu, F., Yu, E. Y. W., Liang, Y., Liang, X., Tian, Y., Wang, J., Huang, F., Zhang, B., Wang, H., Chen, Y. M., & Zheng, J. S. (2022). Associations of dietary diversity with the gut microbiome, fecal metabolites, and host metabolism: results from 2 prospective Chinese cohorts. American Journal of Clinical Nutrition, 116(4), 1049-1058. https://doi.org/10.1093/ajcn/nqac178